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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: REXO4 All Species: 5.76
Human Site: S82 Identified Species: 9.74
UniProt: Q9GZR2 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.31
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9GZR2 NP_065118.2 422 46672 S82 E W L L K Q K S Q A P E K P L
Chimpanzee Pan troglodytes XP_528522 404 44489 P82 E M G S K K K P K I I Q Q N K
Rhesus Macaque Macaca mulatta XP_001101121 422 46500 S82 E W L L K Q K S Q T T E K P L
Dog Lupus familis XP_548392 428 46939 Q80 E L L K Q K T Q A P E K P L V
Cat Felis silvestris
Mouse Mus musculus Q6PAQ4 432 47580 K94 L Q E L L K Q K S Q A A E K P
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508485 438 48720 P91 E L L K Q K T P D R E S G P T
Chicken Gallus gallus XP_001236410 416 45873 P80 G D E N V L K P K S T N K K D
Frog Xenopus laevis Q91560 421 46679 N80 E L L K P K E N Q A L P A T T
Zebra Danio Brachydanio rerio XP_002665913 418 47625 Q98 D A N V N G K Q K P S S P K D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396691 278 32474 R13 E E Q Q K Q C R S K K S A S K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_794891 360 40175 Q81 K K K K K K K Q A M I D T V D
Poplar Tree Populus trichocarpa XP_002300407 274 31114 K9 G S E E Q K K K N P K K K Q K
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q08237 289 32876 K24 P T S N G K N K Q S N R K I R
Red Bread Mold Neurospora crassa Q7S9B7 406 43643 S80 Q T Q S Q P S S Q K P T E E K
Conservation
Percent
Protein Identity: 100 94.3 93.1 68.4 N.A. 67.5 N.A. N.A. 55.7 49 50.7 45 N.A. N.A. 34.1 N.A. 35.7
Protein Similarity: 100 95.5 95.9 77.3 N.A. 77.5 N.A. N.A. 68 63.2 67.3 60.9 N.A. N.A. 47.3 N.A. 53
P-Site Identity: 100 20 86.6 13.3 N.A. 6.6 N.A. N.A. 20 13.3 26.6 6.6 N.A. N.A. 20 N.A. 13.3
P-Site Similarity: 100 46.6 86.6 40 N.A. 26.6 N.A. N.A. 33.3 26.6 46.6 26.6 N.A. N.A. 20 N.A. 33.3
Percent
Protein Identity: 32.2 N.A. N.A. N.A. 28.6 26.7
Protein Similarity: 45 N.A. N.A. N.A. 43.8 47.6
P-Site Identity: 13.3 N.A. N.A. N.A. 13.3 20
P-Site Similarity: 33.3 N.A. N.A. N.A. 26.6 40
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 0 0 0 0 15 15 8 8 15 0 0 % A
% Cys: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % C
% Asp: 8 8 0 0 0 0 0 0 8 0 0 8 0 0 22 % D
% Glu: 50 8 22 8 0 0 8 0 0 0 15 15 15 8 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 15 0 8 0 8 8 0 0 0 0 0 0 8 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 8 15 0 0 8 0 % I
% Lys: 8 8 8 29 36 58 50 22 22 15 15 15 36 22 29 % K
% Leu: 8 22 36 22 8 8 0 0 0 0 8 0 0 8 15 % L
% Met: 0 8 0 0 0 0 0 0 0 8 0 0 0 0 0 % M
% Asn: 0 0 8 15 8 0 8 8 8 0 8 8 0 8 0 % N
% Pro: 8 0 0 0 8 8 0 22 0 22 15 8 15 22 8 % P
% Gln: 8 8 15 8 29 22 8 22 36 8 0 8 8 8 0 % Q
% Arg: 0 0 0 0 0 0 0 8 0 8 0 8 0 0 8 % R
% Ser: 0 8 8 15 0 0 8 22 15 15 8 22 0 8 0 % S
% Thr: 0 15 0 0 0 0 15 0 0 8 15 8 8 8 15 % T
% Val: 0 0 0 8 8 0 0 0 0 0 0 0 0 8 8 % V
% Trp: 0 15 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _